Basic Science/Neurophysiology/Imaging Projects

  • Refinement and Validation of a Portable, Salivary Biosensor of Psychosocial Stress
  • The Oral and Dental Consequences of Methamphetamine Use

Refinement and Validation of a Portable, Salivary Biosensor of Psychosocial Stress
Vivek Shetty, D.D.S., Principal Investigator (vshetty@ucla.edu)
Debra A. Murphy, Ph.D. (dmurphy@mednet.ucla.edu), Co-Investigator
Rachel Fintzy, M.A. (rfintzy@mednet.ucla.edu), Project Director

In this two-phase study, we will test the effectiveness of a salivary biomarker, a small biosensor for salivary analytes. In Phase 1, we will optimize the performance characteristics of the biosensor among 50 healthy controls. In Phase 2, we will conduct functional validation of the biosensor in a cohort of 185 socio-economically vulnerable males with high systemic isolated facial injury.

Refinement and Validation of a Portable, Salivary Biosensor of Psychosocial Stress was funded by the NIH/NIDA to the UCLA Department of Dentistry, Grant 1 U01 DA023815, with collaboration by UCLA ISAP (August 2007 to April 2011).


The Oral and Dental Consequences of Methamphetamine Use
Debra A. Murphy, Ph.D., Principal Investigator (dmurphy@mednet.ucla.edu)
Vivek Shetty, DDS, Dr Med Dent, Co-Investigator
Rachel Fintzy, M.A., Project Director

The primary objectives of this study are: to validate that the rates and patterns of dental caries and oral disease are substantially different in methamphetamine (MA) users than non-MA users; to characterize the relationship between dental consequences, patterns of MA-use and other individual characteristics; and to investigate the extent to which negative self-image among MA-users is associated with a willingness to seek treatment.

The Oral and Dental Consequences of Methamphetamine Use was funded by the NIH, Grant 1 R01 DA025680 to the UCLA Department of Dentistry (April 2010 to January 2014).

Last Updated: 08/17/2011

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