Clinical Provider Quick Tips

Addressing Substance Use in Primary Care Settings

What You Need to Know

Fentanyl Quick Tips

Fentanyl use trends, overdose risks and tools for reducing risk, and relevant medications for opioid use disorders (MOUD) to treat patients within emergency department and primary care settings.

Joseph Friedman, PhD, MPH
Joseph Friedman, PhD, MPH

The US Overdose Crisis: Rapid Shifts in Fentanyl and Novel Synthetic Substances

Description: This brief video describes current trends in overdose, driven by polysubstance combinations with illicit fentanyl and synthetic analogues, and discusses clinical approaches needed to address rising burden of disease.

Presenter: Joseph Friedman, PhD, MPH

Watch Video: Earn CME (.25 credit); Non-Credit Version (20:04 min.)

Course Material: Slides (PDF); Transcript (PDF)


  1. We are in the 'fourth wave' of the US overdose crisis, driven by polysubstance combinations with illicit fentanyls.
  2. Become aware of new health risks to consumers due to rapid shifts in the illicit drug supply.
  3. New clinical approaches are needed to address rising burden of disease.
Candy Stockton-Joreteg, MD, FASAM
Candy Stockton-Joreteg, MD, FASAM

Primary Care/Harm Reduction for People Who Use Fentanyl

Description: This brief video highlights the transferability of skills providers already have treating chronic disease to Fentanyl use, and provides tips and useful information for reducing harm and stigma in primary care.

Presenter: Candy Stockton-Joreteg, MD, FASAM

Watch Video: Earn CME (.25 credit); Non-Credit Version (21:36 min.)

Course Material: Slides (PDF); Transcript (PDF)


  1. If you are a primary care provider who treats chronic diseases, you already have the skill set you need.
  2. Stigma kills; you should be comfortable asking questions and giving practical advice.
Arianna Campbell, PA-C
Arianna Campbell, PA-C

What The Fentanyl! Understanding Fentanyl from the Primary Care Setting

Description: This brief video provides an overview of fentanyl use and the resulting overdose deaths within the past decade, and highlights the benefits of access to naloxone and other harm-reduction and life-saving approaches, including buprenorphine.

Presenter: Arianna Campbell, PA-C

Watch Video: Earn CME (.25 credit); Non-Credit Version (14:45 min.)

Course Material: Slides (PDF); Transcript (PDF)


  1. Primary Care is an essential access point to care for people who use fentanyl.
  2. Become a prescriber! Buprenorphine is a gold standard in combating the overdose epidemic.
  3. Ensure access to naloxone; in-hand naloxone saves lives.
Reb JH Close, M.D.
Reb JH Close, M.D.

Buprenorphine for Patients Using Fentanyl

Description: This brief video highlights the value of using buprenorphine with patients who intentionally or unintentionally are using fentanyl, addresses guidance for inducting patients on buprenorphine in hospital, clinic and home settings, and provides resources to support new prescribers.

Presenter: Reb JH Close, M.D.

Watch Video: Earn CME (.25 credit); Non-Credit Version (16 min.)

Course Material: Slides (PDF); Transcript (PDF)


  1. Fentanyl is prevalent in illicit opioids and greatly increases overdose risk; engaging patients in MOUD treatment increase retention and reduces risk.
  2. Using good practices when starting buprenorphine with fentanyl-using patients will increase treatment success.
  3. Assess and address patients' needs during and after the induction of buprenorphine.

BONUS MATERIAL

Addiction Overview

Description: This video provides a brief overview of substance (particularly opioid) use disorders, including basic neurochemistry. The goal of this course is to increase the knowledge base of health care providers treating patients with opioid use disorders.

Presenter: R. Corey Waller, MD, MS, FACEP, DFASAM

Watch Video: Earn CME (.5 credit); Non-Credit Version (23:29 min.)

*Note: All videos are 508 compliant and include closed captioning.

This series is sponsored by the Department of Healthcare Services in California through the SAMSHA State Opioid Response Grants. All information in the presentations are generated by the presenters and do not reflect the opinions of CA DHCS.